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Morphological Characteristics by Cell Implantation After Spinal Cord Injury in Infarction Region
Objectives: Our research implanted stem cells to reduce behavioral deficiency in rodent animal models of clip compressive surgery inducing spinal cord infarction. Methods/Statistical Analysis: Non-transplanted control injection rats (n=10) were applied to spinal cord injury and administration of PBS (15 μl) after post-damage. Animals were injected with mESC implantation at the 5th day after injured surgery (n=20). Findings: We use the effect of grafted cell to the injured spinal cord region, focusing the use of mouse embryonic cells for regeneration of spinal cord infarction. These morphological characteristics postulated that mESC-graft could reduce the type of cavitations after damage in the SCI model. We also found that Schwann cell and glia cell contain numerous myelinated axons in the middle of the graft. Improvement/Applications: Our research suggests manifest result to prove that graft of stem cell could show behavioral improvement after spinal cord infarction.
Clip-Compression, Embryonic Stem Cell, Graft, Infarction, Spinal Cord.
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