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Antifungal and Antibacterial Activities of Substituted Benzyl 4-Ketohexanoates

Affiliations

  • Institute of Chemical Sciences, Gomal University, Dera Ismail Khan, KPK, Pakistan
  • Medicinal Botanic Centre, PCSIR Laboratories Complex Peshawar, Pakistan
  • University of Sargodha, Punjab, Pakistan
  • Faculty of Pharmacy, Gomal University, Dera Ismail Khan, KPK, Pakistan

Abstract


Present study describes antifungal and antibacterial screening of the previously synthesized novel substituted benzyl 4-ketohexanoates (1-17) against two fungi and two bacteria. All of the substituted benzyl 4-ketohexanoates exhibited antimicrobial activities in terms of inhibition zones and Minimum Inhibitory Concentrations (MICs). Halogens substituted benzyl 4-ketohexanoates in general and Iodinated analogues showed maximum activity in terms of inhibitions zones as well as MICs.

Keywords

Antibacterial, Antifungal, Benzyl 4-ketohexanoates, MICs, Zones of Inhibition.

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