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Issue No:4, Vol.3 |
April - 2010 |
ISSN: 0974-5645 |
| RESEARCH ARTICLES |
Viewers & PDF |
| 21. Chicken egg yolk antibodies (IgY) as an alternative to mammalian antibodies. A. Michael, S. Meenatchisundaram, G. Parameswari, T. Subbraj, R. Selvakumaran and S. Ramalingam (2010) Indian J.Sci.Technol. Vol. 3, Issue 4, pp: 468-474. Domain site: http://www.indjst.org. |
 
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- Abstract
Chicken eggs present an ideal alternative antibody source to mammals, as the IgY in the chicken’s blood is transported
to the egg and accumulates in the egg yolk in large quantities. The existence of an IgG like molecule in avian eggs,
referred to as IgY, has been well documented in recent studies and extensive research has been carried out on its
characterization, production and purification. The yolks of eggs laid by immunized chicken have been recognized as an
excellent source of polyclonal antibodies for over a decade. This simple non invasive approach presents an appealing
alternative to conventional polyclonal antibody production methods. The use of immunoglobulin therapy broadens the
arsenal available to combat pathogens in medicine and IgY is a promising candidate, both as an alternative to
antibiotics and as a useful tool in research and diagnostics.
- Keywords: Chicken antibody IgY; antivenom; passive immunotherapy; Salmonella.
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