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Issue No:5 Vol.4 |
May -2011 |
ISSN: 0974-5645 |
| RESEARCH ARTICLES |
Viewers & PDF |
| 17. Antibacterial evaluation and phytochemical analysis of Medicago sativa L. against some microbial pathogens. A. Doss, V. Parivuguna, M. Vijayasanthi and Sruthi Surendran. Indian J.Sci.Technol. Vol.4, Issue 5, pp: 550-552. |
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- Abstract
Successive solvent extract viz., petroleum ether, chloroform, benzene, methanol, ethanol and water extracts of
Medicago sativa was evaluated for antibacterial activity, against seven important bacterial strains by agar-well
diffusion method. Methanol extract showed significant activity against all the tested bacteria followed by chloroform and
ethanol extract. Benzene and Petroleum ether extracts did not show any significant activity. The antibacterial activity is
more significant in solvent extracts compared to aqueous extract in all the plants indicating that the active principle
responsible for antibacterial activity is more soluble in organic solvents. The results suggest that Medicago sativa is
scientifically validate the use of this plant in the traditional medicine for isolation and characterization of the active
principle for further exploitation in medical microbiology.
- Keywords: Medicago sativa, Antibacterial activity, Methanol, Well diffusion, Phytochemical analysis
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