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Issue No:5 Vol.4 |
May -2011 |
ISSN: 0974-5645 |
| RESEARCH ARTICLES |
Viewers & PDF |
| 2. Activity of commercially available herbal drugs against Salmonella typhi. Syed Aun Muhammad, Zia Ullah Shah, Fawad Ali and Inam-ul-Haq. Indian J.Sci.Technol. Vol.4, Issue 5, pp: 477-480. |
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- Abstract
The uses of herbal drugs are getting popularity in the market of India and Pakistan for the treatment of various
diseases. In this study, the Salmonella typhi (ATCC 19430) susceptibility and sensitivity was evaluated against various
herbal drugs. Seventeen herbal brands including liquid and solid dosage forms claimed to treat typhoid were
purchased in this study. The serial dilutions of these samples were prepared and it was observed that herbal powder
(AY1) sowed activity against Salmonella typhi while the rest of samples were without activity. The brands in liquid state
were comparatively more active as compared to solid brands and in these samples taifax 120ml syrup (MZ1) made
better zone of inhibition against Salmonella typhiwhile typhex plus 60ml (KF3) and temp out syrup (KF4) were less
active. Minimum inhibitory concentration of AY1, MZ1 and KF4 brands were observed at 50μg/ml while the rest of the
brands at this concentration were inactive. Levofloxacin antibiotic was taken as standard and its inhibitory
concentration was 15.62μg/ml. The present study reveals that though herbal drugs are trendy in the market of India
and Pakistan for the treatment of typhoid but it is misfortune to say that most of these drugs are not effective. Therefore
appropriate measures must be taken against such biologically inactive drugs to secure the society.
- Keywords: Salmonella typhi, typhoid, herbal drugs, marketed brands.
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