Indian Journal of
Science and Technology
 
 
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Issue No:9 Vol.4
September-2011
ISSN: 0974-5645
RESEARCH ARTICLES Viewers & PDF
8. Is karyotype beneficial in prenatal non-lethal anomalies?   N. Hephzibah Kirubamani. Indian J.Sci.Technol. Vol.4, Issue 9, pp: 1060-1061. 

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  • Abstract The objective of the study is to evaluate the need   for fetal  karyotyping  after  ultrasonographic  diagnosis  of isolated non lethal anomalies  and to stress  the importance of prenatal counseling. Sixty expectant mothers were chosen to have  detailed  fetal anomalies survey  including   echo were done between 24-28 weeks. The fetuses diagnosed antenately for nonlethal anomalies are subjected to postnatal karyotyping. About twelve cases  of isolated nonlethal anomalies were detected. Various anomalies are intra abdominal cyst, VSD, microcephaly, isolated hydrocephalus, cleft lip, cleft palate, talipes, and abnormal wrist position were detected. Out of twelve cases only one case had abnormal Karyotype and it was Trisomy 18. From this study it is concluded, that in isolated Non-Lethal anomalies with otherwise normal morphology, prenatal testing of karyotyping is not beneficial.
  • Keywords: Antenatal diagnosis, Fetal karyotyping, Health management, Non-lethal anomalies.